Claude's Biology Story Is the Kernels, Not the Binders
Anthropic's Claude sped up 30+ biomolecular models ~4× and cut binder-campaign GPU cost by ~100×. The kernels are the story.
Paper2Agent: Nature turns manuscripts into MCP agents
Nature’s Paper2Agent converts papers and code into tested MCP servers that act like virtual corresponding authors.
The "Learn to Code" Advice Is Outdated. Here's What Actually Matters Now
By Venkata Anirudh Devireddy · Endoblog.dev For over a decade, people who wanted to get into the tech industry were told the best way to do so was to learn to code. This was sound advice back then when coding was the bottleneck in creating software. However, that bottleneck is
AI Agents vs AI Assistants: The Difference Nobody Explains Clearly
By Venkata Anirudh Devireddy · Endoblog.dev They're used interchangeably a lot, but they shouldn't be. The difference between an agent and an assistant tells you about what kind of actions it can perform. An assistant responds. An agent acts. Assistants just respond to your questions. If
Open Weight Models Are Catching Up Faster Than People Realize
By Venkata Anirudh Devireddy · Endoblog.dev There used to be a clear line between the best closed models and the best open weight models. However, the gap between these two categories is starting to shrink, which is something every AI developer should be aware of. What "open weight"
AI Browsers: What They Can Actually Do Right Now
By Venkata Anirudh Devireddy · Endoblog.dev AI browsers went from a novelty to something several companies in the industry are shipping this year alone. So worth understanding what they can do for you. The basic idea of AI browsers is that the browser will show you the website you want
Why Junior Developer Jobs Actually Disappeared
People often say that artificial intelligence killed entry-level developer jobs. While this is true to a certain extent, it's not the complete picture. The numbers For developers between the ages of 22 and 25, there has been a near 20% decrease in the number of available jobs
How to Cold Email a Professor and Actually Get a Reply
By Venkata Anirudh Devireddy · Endoblog.dev I've sent over fifty cold emails to professors and startup founders. Most got ignored. Some got replies. A few turned into actual research affiliations. Here is what separated the two groups. Read something they wrote first Most emails to professors read the
AI Detectors: How They Work and Why People Like Karpathy Don't Trust Them
By Venkata Anirudh Devireddy · Endoblog.dev Every student has had the same moment. You write something yourself, run it through Turnitin out of paranoia, and it comes back flagged as partially AI generated. You didn't use AI. The tool is wrong. And there's no clean way
What Selective CS Programs Actually Look For
By Venkata Anirudh Devireddy · Endoblog.dev A lot of students assume a perfect GPA and a high test score is what gets you into a competitive CS program. Those numbers get you past the first filter. They don't get you the offer. Here's what I'
What "Ambient AI" Actually Means
By Venkata Anirudh Devireddy · Endoblog.dev People throw around the term "AI assistant" for almost anything now. A chatbot is called an assistant. A code autocomplete tool is called an assistant. But most of these tools only exist when you're actively talking to them. Close the
How to Start Contributing to Open Source as a Student
By Venkata Anirudh Devireddy · Endoblog.dev Open source sounds intimidating from the outside. Massive codebases, experienced maintainers, pull requests that get picked apart in review. Most students never try because it feels like something you need to already be good enough for. That's backwards. Contributing is how you